姓 名：王文君
职 称：教授，博导
学科方向：食品科学
电 话：0791-83813655
邮 箱：wwjun9999@jxau.edu.cn
社会兼职：
教育部食品科学与工程类教学指导委员会委员
江西省普通高等学校食品科学与工程类教学指导委员会副主任委员
江西省人民政府学位委员会第二届学科评议组工学（Ⅱ）成员
江西省营养学会副理事长
江西省食品科学技术学会常务理事
中国营养学会会员
《食品科学》杂志、《江西农业大学学报》、《食品安全质量检测学报》编委
教育经历
1991-1995江西农业大学畜牧兽医系畜牧专业 本科
1998-2001 江西农业大学动物遗传育种与繁殖专业 硕士
2003-2006 中国农业大学生物学院生物化学与分子生物学 博士
工作经历
1995-1998 江西省供销社江西远大实业发展有限公司
2001-2005 3522集团的新网站讲师
2005-2011 3522集团的新网站副教授
20011-至今 3522集团的新网站教授
研究领域及方向
分子营养学
食品化学
教授课程
本科生课程：食品化学，食品生物化学
研究生课程：现代食品化学，分子营养学
科研项目
先后主持20多项国家、省部级科研项目， 与企业保持紧密合作，承担多项企业合作项目，累计经费300多万元。主持的课题包括：
1. 江西省自然科学基金重点项目“青钱柳多糖调节尿酸代谢和肠道稳态缓解高尿酸血症的研究” 2023-2025
2. 江西省主要学科学术和技术带头人计划资助项目“青钱柳多糖分子修饰及对树突状细胞免疫调节作用和分子机制研究” 2018-2020
3. 国家自然科学基金项目“基于AMPK信号通路的青钱柳多糖调控脂代谢相关基因DNA甲基化的研究” 2016-2019
4. 国家自然科学基金项目“青钱柳多糖对糖脂代谢的影响及分子机制的研究”，2012-2015
5. 江西现代农业科研协同创新专项“肉鸡产品营养品质评价及调控技术研究”，2017-2019
6. 江西省科技厅重点项目“松针及其提取物调控肉鸡免疫功能关键技术研究及示范” 2016-2018
7. 江西省科技厅重点项目“苜蓿黄酮调控鸡肌肉品质分子机制及绿色饲料添加剂的研制” 2014-2016
8. 江西省高等学校科技落地计划项目“青钱柳多糖对糖脂代谢相关基因DNA甲基化和表达的影响” 2014-2016
近期发表论文：（*表示通讯作者）
1. Yang Zhang, Jing He, Lingli Chen, Wenjun Wang*. Chimonanthus nitens Oliv leaves essential oil alleviates colitis induced by sodium dextran sulfate in BALB/C mice via MAPK/NF-κB/Nrf2 signaling pathway. Journal of Functional Foods, 2024, 11:106095. https://doi.org/10.1016/j.jff.2024.106095
2. Sichen He, Jin Yan, Lingli Chen, Hui Chen, Wenjun Wang*. Structure and in vitro antioxidant and immunomodulatory activity of a glucan from the leaves of Cyclocarya paliurus.Journal of Functional Foods, 2024, 113: 106016. https://doi.org/10.1016/j.jff.2024.106016.
3. Yang Zhang, Meng Zhao, Jing He, Lingli Chen, Wenjun Wang*. In vitro and in vivo immunomodulatory activity of acetylated polysaccharides from Cyclocarya paliurus leaves. International Journal of Biological Macromolecules, 2024, 259( Part 1), 129174 https://doi.org/10.1016/j.ijbiomac.2023.129174
4. Chuanlong Yu, Lingli Chen, Mingsheng Xu, Kehui Ouyang, Hui Chen, Suyun Lin, Wenjun Wang*.The effect of pH and heating on the aggregation behavior and gel properties of beef myosin. LWT - Food Science and Technology, 2024, 191: 115615 https://doi.org/10.1016/j.lwt.2023.115615.
5. Jin Yan, Sichen He, Lingli Chen, Hui Chen, Wenjun Wang*. Characterization, antioxidant and antibacterial activities of gelatin-chitosan edible coated films added with Cyclocarya paliurus flavonoids. International Journal of Biological Macromolecules, 2023,253: 127664 https://doi.org/10.1016/j.ijbiomac.2023.127664
6. Wenya Meng, Suyun Lin, Kehui Ouyang, Lingli Chen, Ying Zhang, and Wenjun Wang*. Screening and Inhibition Mechanism of Xanthine Oxidase Inhibitors in Ethanolic Extracts of Chimonanthus salicifolius Hu Leaves. Chemistry & Biodiversity, 2023, 20, e202200480 http://doi.org/10.1002/cbdv.202200480
7. Wenya Meng, Lingli Chen, Kehui Ouyang, Suyun Lin, Yang Zhang, Jing He, Wenjun Wang*. Chimonanthus nitens Oliv Leaves flavonoids alleviate hyperuricemia by regulating uric acid metabolism and intestinal homeostasis in mice. Food Science and Human Wellness, 2023, 12(6): 2440-2450 (8.022) http://doi.org/10.1016/j.fshw.2023.03.011
8. Zedong Zhang, Wanting Hu, Qiuyue Xie, Yuezhe Shi, Yutong Zhao, Yaxin Deng, Jiaxin He, Xia Wu, Yu Zhang, Wenqi Zhang, Pengjun Liu, Hao Yang, Wenjun Wang*. Efficient decolorization of melanoidin in raw molasses wastewater by thermophilic esterase in actual extreme conditions. Bioresource Technology, 2023, 382: 129191
9. Huan Zhou, Lingli Chen, Kehui Ouyang, Qingfeng Zhang, Wenjun Wang*. Antibacterial activity and mechanism of flavonoids from Chimonanthus salicifolius S. Y. Hu. and its transcriptome analysis against Staphylococcus aureus. Frontiers in Microbiology, 2023, 13:1103476. https://doi:10.3389/fmicb.2022.1103476
10. Hui-Hui Xiong, Su-Yun Lin, Ling-Li Chen, Ke-Hui Ouyang, Wen-Jun Wang*. The Interaction between Flavonoids and Intestinal Microbes: A Review. Foods, 2023, 12, 320. https://doi.org/10.3390/foods12020320
11. Yang Zhang, Yantian Tang, Lei Cai, Jing He, Lingli Chen, Kehui Ouyang, Wenjun Wang*. Chimonanthus nitens Oliv Polysaccharides Modulate Immunityand Gut Microbiota in Immunocompromised Mice. Oxidative Medicine and Cellular Longevity, 2023,Volume 2023, Article ID 6208680, https://doi.org/10.1155/2023/6208680
12. Wenya Meng, Zitong Zhao, Lingli Chen, Suyun Lin, Yang Zhang, Jing He, Kehui Ouyang*, Wenjun Wang*. Total Flavonoids from Chimonanthus nitens Oliv. Leaves Ameliorate HFD-Induced NAFLD by Regulating the Gut–Liver Axis in Mice. Foods, 2022, 11(14), 2169; https://doi.org/10.3390/foods11142169
13. Jing He, Yang Zhang, Kehui Ouyang, Lingli Chen, Wenya Meng, Ying Zhang, Wenjun Wang*. Extraction, chemical composition and protective effect of essential oil from Chimonanthus nitens Oliv. leaves on dextran sodium sulfate - induced colitis in mice. Oxidative Medicine and Cellular Longevity, (7.310) Volume 2022, Article ID 9701938, 15 pages, 2022 https://doi.org/10.1155/2022/9701938
14. Xiang Li, Si Chen, Ke-Hui Ouyang, Wen-Jun Wang*. Effects of polysaccharides from Yingshan Yunwu tea on free amino acids, flavor nucleotides and antioxidant abilities in chickens.Research in Veterinary Science, 2022, 149: 11–20 https://doi.org/10.1016/j.rvsc.2022.06.003
15. Yi Han, Yang Zhang, Kehui Ouyang, Lingli Chen, MengZhao, Wenjun Wang*. Sulfated Cyclocarya paliurus polysaccharides improve immune function of immunosuppressed mice by modulating intestinal microbiota. International Journal of Biological Macromolecules, 2022, 212: 31-42 https://doi.org/10.1016/j.ijbiomac.2022.05.110
16. Lin Luo#, Jie Ni#, Mengyun Zhou#, Chunyi Wang, Wen Wen, Jingjie Jiang, Yongran Cheng, Xingwei Zhang, Mingwei Wang*, Wenjun Wang*. Food safety knowledge, attitudes, and self-reported practices among medical staff in China before, during and after the COVID-19 pandemic. Risk Management and Healthcare Policy, 2021, 14: 5027–5038 https://doi.org/10.2147/RMHP.S339274
17. Ling-Li Chen, Wen-Jun Wang*. p53 regulates lipid metabolism in cancer. International Journal of Biological Macromolecules, 2021, 192: 45–54 https://doi.org/10.1016/j.ijbiomac.2021.09.188
18. Yang Zhang, Yi Han, Jing He, Kehui Ouyang, Meng Zhao, Lei Cai, Zitong Zhao,Wenya Meng, Lingli Chen, Wenjun Wang*. Digestive properties and effects of Chimonanthus nitens Oliv polysaccharides on antioxidant effects in vitro and in immunocompromised mice. International Journal of Biological Macromolecules, 2021, 85: 306–316 https://doi.org/10.1016/j.ijbiomac.2021.06.114
19. ZhanweiYang, JingZhao, Jing'enLi, JinWang, WenjunWang∗. Genome-wide DNA methylation profiling of high-fat emulsion-induced hyperlipidemia mice intervened by a polysaccharide from Cyclocarya paliurus (Batal) Iljinskaja. Food and Chemical Toxicology, 2021, 112230 https://doi.org/10.1016/j.fct.2021.112230
20. Yi Han, Meng Zhao, Kehui Ouyang, Si Chen, Yang Zhang, Xin Liu, Qi An, Zitong Zhao,Wenjun Wang*. Sulfated modification, structures, antioxidant activities and mechanism ofCyclocarya paliurus polysaccharides protecting dendritic cells againstoxidant stress. Industrial Crops and Products, 2021, 164: 113353 https://doi.org/10.1016/j.indcrop.2021.113353
21. Meng-Zhao, Yi-Han, Jing'en Li, Qi-An, Ximei Ye, Xiang-Li, Zitong Zhao, Yang-Zhang, Jing-He, Qihuan,Deng, Wenjun Wang*. Structural characterization and antioxidant activity of an acetylated Cyclocarya paliurus polysaccharide (Ac-CPP0.1). International Journal of Biological Macromolecules.2021, 171:112-122https://doi.org/10.1016/j.ijbiomac.2020.12.201
22. Qi An, Ximei Ye, Yi Han, Meng Zhao, Si Chen, Xin Liu, Xiang Li, Zitong Zhao, Yang Zhang,Kehui Ouyang, Wenjun Wang*. Structure analysis of polysaccharides purified from Cyclocarya paliurus with DEAE-Cellulose and its antioxidant activity in RAW264.7 cells, International Journal of Biological Macromolecules.2020, 157: 604-615 https://doi.org/10.1016/j.ijbiomac.2019.11.212
23. Yi Han, Kehui Ouyang, Jingen Li, Xin Liu, Qi An, Meng Zhao, Si Chen, Xiang Li, Ximei Ye, Zitong Zhao, Lei Cai, Wenjun Wang*. Sulfated modification, characterization, immunomodulatory activities and mechanism of the polysaccharides from Cyclocarya paliuruson dendritic cells. International Journal of Biological Macromolecules. 2020, 159: 108–116 https://doi.org/10.1016/j.ijbiomac.2020.04.265
24. Ximei Ye, Qi An, Si Chen, Xin Liu, Ning Wang, Xiang Li, Meng Zhao, Yi Han, Zitong Zhao, Kehui Ouyang, Wenjun Wang*. The structural characteristics, antioxidant and hepatoprotection activities of polysaccharides from Chimonanthus nitens Oliv. Leaves, International Journal of Biological Macromolecules. 2020, 156: 1520-1529 https://doi:10.1016/j.ijbiomac.2019.11.200
25. Xin Liu, Yangping Wen, Wenjun Wang*, Zitong Zhao, Yi Han, Kaijie Tang, Dan Wang*. Nanobody-based electrochemical competitive immunosensor for the detection of AFB1 through AFB1-HCR as signal amplifier. Microchimica Acta 2020,187(6): 352: 352. https://doi.org/10.1007/s00604-020-04343-2
26. Lei-Xiong#, Ke-Hui Ouyang#, Hui-Chen, Zhan-Wei Yang, Wen-Bing Hu, Ning-Wang, Xin-Liu, Wen-Jun Wang*. Immunomodulatory effect of Cyclocarya paliurus polysaccharide in cyclophosphamide induced immunocompromised mice. Bioactive Carbohydrates and Dietary Fibre, 2020, 24, 100224, https://doi.org/10.1016/j.bcdf.2020.100224
27. Jingen Li, Qihuan Deng, XiaoyunYu, WenjunWang*. Structural studies of a new fraction obtained by gradient ethanol precipitation from Acacia seyal gum. Food Hydrocolloids,2020, 105932 https://doi.org/10.1016/j.foodhyd.2020.105932
28. Xiang-Li, Si-Chen, Zi-Tong Zhao, Meng-Zhao, Yi-Han, Xi-Mei Ye, Qi-An, Ke-Hui Ouyang*, Wen-Jun Wang*. Effects of polysaccharides from Yingshan Yunwu tea on meat quality, immune status and intestinal microflora in chickens. International Journal of Biological Macromolecules. 2020, 155: 61-70https://doi.org/10.1016/j.ijbiomac.2020.03.198
29. Ning Wang, Xin Liu, Jingen Li, Qingfeng Zhang, Xiang Li, Qi An, Ximei Ye, Zitong Zhao, Lei Cai, Yi Han, Meng Zhao, Wang Wenjun* Antibacterial mechanism of the synergistic combination betweenstreptomycin and alcohol extracts from the Chimonanthus salicifolius S. Y.Hu. Leaves. Journal of Ethnopharmacology, 2020, 250: 112467 https://doi.org/10.1016/j.jep.2019.112467
30. Si Chen, Xiang Li, Xin Liu, Ning Wang, Qi An, Xi Mei Ye, Zi Tong Zhao, Meng Zhao, Yi Han, Ke Hui Ouyang*, and Wen Jun Wang*. Investigation of Chemical Composition, Antioxidant Activity, and the Effects of Alfalfa Flavonoids on Growth Performance. Oxidative Medicine and Cellular Longevity, 2020, Volume 2020, 8569237 https://doi.org/10.1155/2020/8569237
31. Xiang-Li, Si-Chen, Jing-En Li, Ning-Wang, Xin-Liu, Qi-An, Xi-Mei Ye, Zi-Tong Zhao, Meng-Zhao, Yi-Han, Ke-Hui Ouyang*, Wen-Jun Wang*.Chemical composition and antioxidant activities of polysaccharides from Yingshan Cloud Mist Tea. Oxidative Medicine and Cellular Longevity, 2019, Volume 2019, Article ID 1915967https://doi.org/10.1155/2019/1915967
32. Lei-Xiong#, Wen-Bing Hu#, Zhan-Wei Yang, Hui-Chen, Wang-Ning, Liu-Xin, Wen-Jun Wang*. Enzymolysis-ultrasonic assisted extraction of flavanoid from Cyclocarya paliurus (Batal) Iljinskaja: HPLC profile, antimicrobial and antioxidant activity. Industrial Crops & Products, 2019, 130: 615–626 https://doi.org/10.1016/j.indcrop.2019.01.027
33. Zhanwei Yang, Jing Zhao, Jin Wang, Jingen Li, Kehui Ouyang*, Wenjun Wang*. Effects of Cyclocarya paliurus polysaccharide on lipid metabolism-related genes DNA methylation in rats. International Journal of Biological Macromolecules. 2019, 123(2): 343-349 https://doi.org/10.1016/j.ijbiomac.2018.11.110
专利获得情况：
Use ethanolic extracts of Chimonanthus Salicifilius S. Y. Hu. in preparation of untibiotic-modulating agents，专利授权号：2020102144，澳大利亚，2020，
一种绵羊瘤胃上皮细胞的分离培养方法，专利授权号：ZL 2017 1 0363364.X，2020
一种节能型智能化滚筒式茶叶杀青及炒干装置，专利授权号：ZL 2018 2 1602376.X，2018
一种优质肉鸡用饲料添加剂的制备及其应用，专利授权号：ZL20150366994.3，2018
咖啡酰奎宁酸制备方法与应用，ZL201310133693.7，2015
一种祛痰止咳组合物及其制备方法，专利授权号：ZL 201210271132.9，2015
一种放牧牛用饲草补料器 ZL 2015 2 1012895.7，2016
获得奖励
青钱柳综合开发与利用研究江西省科技进步二等奖(第5) 2007
青钱柳综合开发与利用研究江西省高等学校科技成果奖二等奖(第4) 2007
猪生长发育性状候选基因遗传变异的研究江西省高等学校科技成果奖三等奖(第1) 2007
中国食品产业科研创新发展“杰出科研人才奖”，中国食品杂志社，2015
畜牧业对鄱阳湖草地群落及生态系统的影响，中国草业科技奖三等奖，第二，2015
指导的研究生分别于2013、2016-2020年获得省级优秀硕士学位论文
