姓 名:郑国栋
职 称:教授
学科方向:食品营养与功能
研究领域及方向:天然产物分离与能量代谢和降脂减肥功效
邮 箱:zrs150716@aliyun.com
教育经历:
教育经历(按时间倒序排序):
2001.04-2005.03 日本国立岐阜大学 博士,导师:潘场公雄
1999.04-2001.03 日本国立静冈大学 硕士,导师:茶山和敏
1988.09-1992.07 福建农学院 学士
工作经历
2015.12至今 江西农业大学 教授
2007.08-2015.12 江西农业大学 副教授
2006.04-2007.07 日本农水公司 课长
2005.04-2006.03 日本国立静冈大学 博士后,合作导师:茶山和敏
1998.10-1999.03 日本国立静冈大学 访问学者,合作导师:茶山和敏
1992.07-1998.09 福建省长乐市梅花中学 教师
教授课程
食品生物化学、食品化学、食品毒理学等
主持科研项目
1、主持国家自然基金地区项目,《基于菝葜多酚类化合物对肠道菌群代谢产物与脂类代谢的相关性研究》(2021.01-2024.12)项目编号:82060165,经费,40.8万元
2、主持国家自然基金地区项目,《基于AMPK信号通路研究菝葜黄酮提取及调控脂类代谢的分子机制》(2018.01-2021.12)项目编号:81760157,经费,38.4万元
3、主持国家自然基金地区项目,《儿茶素和咖啡碱组合对小鼠和3T3-L1 细胞的脂肪代谢分子机制的研究》(2012.01-2015.12)项目编号:31160320,经费,42万元,已结题
4、主持江西省科技厅科技支撑重大项目,《夏秋茶品质提升及综合利用》(2016.01-2017.12)项目编号:S2016NYZDF0071,经费,50万元
5、主持江西省星火计划项目,《万亩有机茶产品提升机加工》(2014.01-2015.12)项目编号:20141BBF61088,经费,35万元,已结题
6、主持完成江西省自然科学基金项目:《咖啡碱和绿原酸对高脂饮食诱导肥胖小鼠脂肪代谢相关基因和蛋白表达的影响》(2014.01-2015.12)项目编号:20142BAB204003,经费,5万元,已结题
奖励
郑国栋,张清峰,黎冬明。植物功能成分分离鉴定及降脂减肥作用的研究,江西省自然科学奖,三等奖,2013
近年来以第一或通讯作者发表的主要论文:
1、Licong Yang#, Yanping Zhu, Shusheng Zhong and Guodong Zheng*. Astilbin lowers the effective caffeine dose for decreasing lipid accumulation via activating AMPK in high-fat diet-induced obese mice [J]. Jouenal of the Science of Food and Agriculture, 2020, DOI 10.1002/jsfa.10669 (SCI, IF=2.614)
2、Meng Xu#, Licong Yang#, Yanping Zhu, Mingfu Liao, Lulu Chu, Xin Li, Lezhen Lin, Guodong Zheng*. Collaborative effects of chlorogenic acid and caffeine on lipid metabolism via AMPKα-LXRα/SREBP-1c pathway in High-Fat Diet-Induced obese mice [J]. Food & Function, 2019, 10: 7489-7497. (SCI, IF=4.171) DOI: 10.1039/C9FO00502A
3、Meng Xu#, Hui Xue, Xin Li, Yan Zhao, Lezhen Lin, Licong Yang*, Guodong Zheng*. Chemical composition, antibacterial properties, and mechanism of Smilax china L. polyphenols [J]. Applied Microbiology and Biotechnology, 2019, 103: 9013-9022. (SCI, IF=3.67)
4、Lulu Chu#, Licong Yang*, Jingen Li, Lezhen Lin, Guodong Zheng*. Effect of Smilax china L. starch on the gel properties and interactions of calcium sulfate-induced soy protein isolate gel [J]. International Journal of Biological Macromolecules, 2019, 135: 127-132. (SCI, IF=5.162)
5、Lulu Chu#, Licong Yang*, Lezhen Lin, Jing Wei, Na Wang, Meng Xu, Gaoxiang Qiao, Guodong Zheng*. Chemical composition, antioxidant activities of polysaccharide from Pine needle (Pinus massoniana) and hypolipidemic effect in high-fat diet-induced mice [J]. International Journal of Biological Macromolecules, 2019, 125: 445-452. (SCI, IF=5.162)
6、Licong Yang#, Yan Zhao, Yongfang Pan, Dongming Li, Guodong Zheng*. Dietary Supplement of Smilax china L. Ethanol Extract Alleviates the Lipid Accumulation by Activating AMPK pathways in High-Fat Diet Fed Mice [J]. Nutrition & Metabolism, 2019, 16, 6. doi.org/10.1186/s12986-019-0333-z (SCI, IF=3.599)
7、Licong Yang#, Na Wang, Guodong Zheng*. Enhanced effect of combining chlorogenic acid on selenium nanoparticles in inhibiting amyloid β aggregation and reactive oxygen species formation In Vitro[J]. Nanoscale Research Letters, 2018, 13:303 (SCI, IF=3.125)
8、Licong Yang#, Wenjun Wang, Jiguang Chen, Na Wang, Guodong Zheng*. A comparative study of resveratrol and resveratrol-functional selenium nanoparticles: Inhibiting amyloid β aggregation and reactive oxygen species formation properties[J]. Journal of Biomedical Materials Research Part A, 2018, 106A: 3034-3041. (SCI, IF=3.231)
9、Ji-Luan Liu#, Li-Cong Yang#, Xiao-Juan Zhu, Wen-Jun Wang, Guo-Dong Zheng*. Combinational effect of pine needle polysaccharide and Kudzu flavonoids on cell differentiation and fat metabolism in 3T3-L1 cells[J]. Food Science and Technology Research, 2018, 24 (5), 903-910 (SCI, IF=0.379)
10、Yan Zhao#, Licong Yang#, Zhanwang Huang, Lezhen Lin, Guodong Zheng*, Synergistic effects of caffeine and catechins on lipid metabolism in chronically fed mice via the AMP activated protein kinase signaling pathway[J]. European Journal of Nutrition, 2017, 56(7): 2309-2318. (SCI, IF=4.423)
11、Xiaojuan Zhu#, Licong Yang, Lezhen Lin, Guodong Zheng*. Combination therapy with catechins and caffeine inhibits fat accumulation in 3T3-L1 cells[J]. Experimental and Therapeutic Medicine, 2017, 13, 688-694(SCI,IF=1.410)
12、Guodong Zheng*, Lezhen Lin, Shusheng Zhong, Qingfeng Zhang, Dongming Li. Effects of puerarin on lipid accumulation and metabolism in high-fat diet-fed mice [J]. PLOS One, 2015, 10(3): e0122925.(SCI, IF=3.234)
13、Guodong Zheng*, Yangyang Qiu, Qingfeng Zhang, Dongming Li. Chlorogenic acid and caffeine in combination inhibit fat accumulation by regulating hepatic lipid metabolism-related enzymes in mice[J]. British Journal of Nutrition, 2014, 112(6), 1034-1040.(SCI、IF=3.453)